The College of Veterinary Medicine at Iowa State University is accepting applications for an Assistant Scientist III in the Veterinary Diagnostic Laboratory (VDL). The ISU VDL is a full-service veterinary diagnostic laboratory engaged daily in missions of service, instruction, and research. The laboratory receives more than 80,000 submissions from veterinarians and researchers annually.
This position will conduct very complex experiments using non-standard procedures for chemical analyses on a wide variety of biological specimens using state-of-the-art liquid chromatography/mass spectrometry (LC/MS) and gas chromatography/mass spectrometry (GC/MS) technologies for both clinical diagnostic and research applications. The position uses these advanced analytical chemistry tools to detect and quantitate drugs, toxins, and a myriad of physiologically-impacting compounds in clinical specimens submitted to the ISU VDL by practicing veterinarians, researchers, exhibition or gaming commissions, and industry partners. This work will include researching and developing appropriate analyte isolation methods for subsequent characterization by LC/MS and GC/MS, as well as developing LC/MS and GC/MS methods that will optimize detection of these analytes. The individual will interpret and communicate the results to the ISU VDL clientele, prepare documents for publication and funding proposals, and develop major experimental methods for analyte isolation from biological matrices based on information from a wide variety of sources including literature reports, industry experience, and contact with colleagues in animal pharmacokinetics, veterinary toxicology, and the drug detection industries. The individual will maintain equipment, establish and follow maintenance procedures, train others on equipment use and procedures, and oversee and train entry-level scientists and students working in the laboratory.
The successful candidate will have the ability to communicate effectively through speaking and writing, write reports to clearly explain and document clinical results and research findings, possess great attention to detail in day-to-day operation of sensitive instrumentation, and the ability to develop, validate, document, and successfully implement analytical methods for clinical diagnostic and research applications.
Required Education and Experience
Bachelor's degree and 5 years of related experience; OR a Master's degree and 3 years of related experience; or a Ph.D. or other professional degree and related experience.Supplemental Required Education and Experience
Degree must be in Chemistry, Toxicology, Biochemistry, Biology, Environmental Science or a closely related field.
Experience must include work in Mass Spectrometry.Preferred Education and Experience
- PhD degree
- 5 years of experience in analyte detection by Mass Spectrometry.
- Advanced knowledge of chemistry and how pH, polarity, and molecular structure and functional groups affect the ability to isolate analytes.
- Advanced knowledge of appropriate equipment and instrumentation of manual and automated sample extraction, including solid phase extraction (SPE) and liquid/liquid extraction (LLE)